1. Analyze the role of histone modifications and chromatin remodeling in regulating chromosome structure and function. How do alterations in histone acetylation, methylation, or phosphorylation affect gene expression, and what is their significance in cancer development and progression ?

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Histone modifications and chromatin remodeling play crucial roles in regulating chromosome structure and function by altering the accessibility of DNA to transcription factors and other regulatory pro... View the full answer