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If an antibiotic is taken orally, only a fraction of the antibiotic is actually absorbed in the bloodstream. This fraction is called bioavailability of the dose. Suppose that for a specific antibiotic, when x mg is taken orally, only 70% of the dose is absorbed, that is the 7 bioavailability can be expressed as X. 10 Now, if h mg of antibiotic enters the bloodstream, the amount eventually absorbed at the site of the infection 5h is g(h) = mg. h+5 Finally, if g mg is absorbed into the site of the infection, the number of surviving bacteria is given by 3300 f(g) = CFU (colony forming units). 9+g a) If a dose of 4 mg is given orally, compute the amount of antibiotic absorbed at the site of infection. mg. Round to 1 decimal place as needed. Answer: b) If an amount of 8 mg enters the bloodstream, compute the amount that is eventaully absorbed at the site of the infection. Answer: mg. Round to 1 decimal place as needed. c) If a dose of 6 mg is injected directly into the bloodstream compute the number of surviving bacteria. Answer: Round to the nearest whole number. If an antibiotic is taken orally, only a fraction of the antibiotic is actually absorbed in the bloodstream. This fraction is called bioavailability of the dose. Suppose that for a specific antibiotic, when x mg is taken orally, only 70% of the dose is absorbed, that is the 7 bioavailability can be expressed as X. 10 Now, if h mg of antibiotic enters the bloodstream, the amount eventually absorbed at the site of the infection 5h is g(h) = mg. h+5 Finally, if g mg is absorbed into the site of the infection, the number of surviving bacteria is given by 3300 f(g) = CFU (colony forming units). 9+g a) If a dose of 4 mg is given orally, compute the amount of antibiotic absorbed at the site of infection. mg. Round to 1 decimal place as needed. Answer: b) If an amount of 8 mg enters the bloodstream, compute the amount that is eventaully absorbed at the site of the infection. Answer: mg. Round to 1 decimal place as needed. c) If a dose of 6 mg is injected directly into the bloodstream compute the number of surviving bacteria. Answer: Round to the nearest whole number.
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Related Book For
Elementary Principles of Chemical Processes
ISBN: 978-1119498759
4th edition
Authors: Richard M. Felder, ? Ronald W. Rousseau, ? Lisa G. Bullard
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