Assume that acetyl CoA containing a 14C isotopic label in the carboxyl carbon atom is used as
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Assume that acetyl CoA containing a 14C isotopic label in the carboxyl carbon atom is used as starting material for the biosynthesis of mevalonate, as shown in figure. At what positions in mevalonate would the isotopic labelappear?
Transcribed Image Text:
Нзс, он H3C OH ATP ADP ATP ADP CH20-PO CH2OH н ннн H H H H Mevalonate 5-phosphate (R)-Mevalonate ADP, P. ATP Co2 CHз Hас о-н CH20-POPO CH2 CH20-POPO- H2C H H H H Mevalonate 5-diphosphate Isopentenyl diphosphate
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