A group of 30 postmenopausal women were given oral conjugated estrogen for one month. Plasma levels of

Question:

A group of 30 postmenopausal women were given oral conjugated estrogen for one month. Plasma levels of plasminogen-activator inhibitor type 1 (PAI-1) went down for 22 of the women, but went up for 8 women.15 The P-value for a sign test, with a non directional alternative, is 0.016.
(a) State the null and alternative hypotheses in context.
(b) If α= 0.10, what is your conclusion regarding H0?