A method for the determination of the corticosteroid methylprednisolone acetate in solutions obtained from pharmaceutical preparations yielded
Question:
A method for the determination of the corticosteroid methylprednisolone acetate in solutions obtained from pharmaceutical preparations yielded a mean value of 3.7 mg mL-1 with a standard deviation of 0.3 mg mL-1. For quality control purposes, the relative uncertainty in the concentration should be no more than 3%. How many samples of each batch should be analyzed to ensure that the relative standard deviation does not exceed 7% at the 95% confidence level?
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