Question: Certain microorganisms with an incomplete citric acid cycle decarboxylate (- ketoglutarate to produce succinate semialdehyde. A dehydrogenase then converts succinate semialdehyde to succinate. These reactions

Certain microorganisms with an incomplete citric acid cycle decarboxylate (- ketoglutarate to produce succinate semialdehyde. A dehydrogenase then converts succinate semialdehyde to succinate.

These reactions can be combined with other standard citric acid cycle reactions to create a pathway from citrate to oxaloacetate. Compare the ATP and reduced cofactor yield of the standard and alternate pathways.

COO CH, CH2 C=O COO -Ketoglutarate COo NAD+ NADH CH2 CH2 COO COO CH2 CH2 CO2 Succinate semialdehyde Succinate

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