Enzymes are often described as following the two-step mechanism: ES -- E + P (slow) Where E
Question:
ES --†’ E + P (slow)
Where E = enzyme, S = substrate, ES = enzyme - substrate complex, and P = product.
(a) If an enzyme follows this mechanism, what rate law is expected for the reaction?
(b) Molecules that can bind to the active site of an enzyme but are not converted into product are called enzyme inhibitors. Write an additional elementary step to add into the preceding mechanism to account for the reaction of E with I, an inhibitor?
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Related Book For
Chemistry The Central Science
ISBN: 978-0321696724
12th edition
Authors: Theodore Brown, Eugene LeMay, Bruce Bursten, Catherine Murphy, Patrick Woodward
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