Question: Histone genes are unusual among eukaryotic genes because they do not have introns, and histone mRNAs do not have poly (A) tails (see Chapter 24).

Histone genes are unusual among eukaryotic genes because they do not have introns, and histone mRNAs do not have poly (A) tails (see Chapter 24). Moreover, in almost all eukaryotes, histone genes are arranged in multiple tandem domains, each domain carrying one copy of each of the ﬁve histone genes. Explain these features in terms of the special requirements for histone synthesis.

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