Clinical Trial of Tamiflu Clinical trials involved treating flu patients with Tamiflu (oseltamivir phosphate), which is a medicine intended to attack the influenza virus and stop it from causing flu symptoms. Among 724 patients treated with Tamiflu, 72 experienced nausea as an adverse reaction. Use a 0.05 significance level to test the claim that the rate of nausea is greater than the 6% rate experienced by flu patients given a placebo. Does nausea appear to be a concern for those given the Tamiflu treatment? Testing Claims About Proportions. In Exercises 9–28, test the given claim. Identify the null hypothesis, alternative hypothesis, test statistic, P-value, or critical value(s), then state the conclusion about the null hypothesis, as well as the final conclusion that addresses the original claim. Use the P-value method unless your instructor specifies otherwise. Use the normal distribution as an approximation to the binomial distribution, as described in Part 1 of this section.