Does Aspirin Prevent Heart Disease? In a trial designed to test the effectiveness of aspirin in preventing

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Does Aspirin Prevent Heart Disease? In a trial designed to test the effectiveness of aspirin in preventing heart disease, 11,037 male physicians were treated with aspirin and 11,034 male physicians were given placebos. Among the subjects in the aspirin treatment group, 139 experienced myocardial infarctions (heart attacks). Among the subjects given placebos, 239 experienced myocardial infarctions (based on data from “Final Report on the Aspirin Component of the Ongoing Physicians’ Health Study,” New England Journal of Medicine, Vol. 321: 129–135). Use a 0.05 significance level to test the claim that aspirin has no effect on myocardial infarctions.

a. Test the claim using a hypothesis test.

b. Test the claim by constructing an appropriate confidence interval.

c. Based on the results, does aspirin appear to be effective?

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Biostatistics For The Biological And Health Sciences

ISBN: 9780134039015

2nd Edition

Authors: Marc Triola, Mario Triola, Jason Roy

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