LDL and fiber. A cross-over trial compared serum cholesterol in 13 subjects while on moderate-fiber diets and while on high-fiber diets.

The study concluded that the high-fiber diet reduced very-lowdensity lipoprotein cholesterol by 12.5% (P = 0.01).d A dietician criticizes the study by saying that very-low-density lipoproteins vary greatly from day to day and that the results could merely reflect a random variation. Explain how the P-value of 0.01 addresses this objection.