One of the objectives of a study by Mulloy and McNicholas (A-26) was to compare ventilation and gas exchange during sleep and exercise in chronic obstructive pulmonary disease

(COPD). The investigators wished also to determine whether exercise studies could aid in the prediction of nocturnal desaturation in COPD. Subjects (13 male, 6 female) were ambulatory patients attending an outpatient respiratory clinic. The mean age of the patients, all of whom had severe, stable COPD, was 64.8 years with a standard deviation of 5.2. Among the data collected were measurements on the following variables:

Age PaO2 PaCO2 FEV1 Lowest Sleep Sleep Sleep (years) BMI (mm Hg) (mm Hg) (% Predicted) Ex.
69 25.78 68.25 43.8 32 85 90.91 79 13 57 22.13 83.25 43.725 20 88 94.39 86 9.5 74 26.74 57.75 51 33 75 89.89 80 14.11 63 19.07 78 44.175 36 81 93.95 82 13 64 19.61 90.75 40.35 27 90 95.07 92 4 73 30.30 69.75 38.85 53 87 90 76 18 63 26.12 51.75 46.8 39 67 69.31 46 34.9 62 21.71 72 41.1 27 88 87.95 72 22 67 24.75 84.75 40.575 45 87 92.95 90 2.17 57 25.98 84.75 40.05 35 94 93.4 86 8.45 66 32.00 51.75 53.175 30 83 80.17 71 16