Pellegrino et al. (A-12) hypothesized that maximal bronchoconstriction can be predicted from the bronchomotor effect of deep inhalation and the degree of airway sensitivity to methacholine

(MCh). One group of participants consisted of 26 healthy or mildly asthmatic subjects (22 males, 4 females) who had limited bronchoconstriction to inhaled MCh. The mean age of the patients was 31 years with a standard deviation of 8. There was one smoker in the group. Among the data collected on each subject were the following observations on various lung function measurement variables: