Research by Huhtaniemi et al. (A-19) focused on the quality of serum luteinizing hormone (LH)

during pubertal maturation in boys. Subjects, consisting of healthy boys entering puberty (ages 11 years 5 months to 12 years), were studied over a period of 18 months. The following are the concentrations

(IU/L) of bioactive LH (B-LH) and immunoreactive LH (I-LH) in serum samples taken from the subjects. Only observations in which the subjects’ B/I ratio was greater than 3.5 are reported here.

I-LH B-LH I-LH B-LH

.104 .37 .97 3.63

.041 .28 .49 2.26

.124 .64 1 4.55

.808 2.32 1.17 5.06

.403 1.28 1.46 4.81

.27 .9 1.97 8.18

.49 2.45 .88 2.48

.66 2.8 1.24 4.8

.82 2.6 1.54 3.12 I-LH B-LH I-LH B-LH 1.09 4.5 1.71 8.4 1.05 3.2 1.11 6 .83 3.65 1.35 7.2 .89 5.25 1.59 7.6 .75 2.9