Research by Huhtaniemi et al. (A-19) focused on the quality of serum luteinizing hormone (LH) during pubertal maturation in boys. Subjects, consisting of healthy boys entering puberty (ages 11 years 5 months to 12 years), were studied over a period of 18 months. The following are the concentrations

(IU/L) of bioactive LH (B-LH) and immunoreactive LH (I-LH) in serum samples taken from the subjects. Only observations in which the subjects’ B/I ratio was greater than 3.5 are reported here.

I-LH B-LH I-LH B-LH

.104 .37 .97 3.63

.041 .28 .49 2.26

.124 .64 1 4.55

.808 2.32 1.17 5.06

.403 1.28 1.46 4.81

.27 .9 1.97 8.18

.49 2.45 .88 2.48

.66 2.8 1.24 4.8

.82 2.6 1.54 3.12 1.09 4.5 1.71 8.4 1.05 3.2 1.11 6

.83 3.65 1.35 7.2

.89 5.25 1.59 7.6

.75 2.9