The purpose of a study by researchers at the Cleveland (Ohio) Clinic (A-6) was to determine if the use of Flomax® reduced the urinary side effects commonly experienced by patients following brachytherapy (permanent radioactive seed implant) treatment for prostate cancer. The following table shows the American Urological Association (AUA) symptom index scores for two groups of subjects after 8 weeks of treatment. The higher the AUA index, the more severe the urinary obstruction and irritation.

AUA Index (Flomax®) AUA Index (Placebo)

1 5 11 1 6 12 1 5 11 1 6 12 2 6 11 2 6 13 2 6 11 2 6 14 2 7 12 2 6 17 2 7 12 3 7 18 3 7 13 3 8 19 3 7 14 3 8 20 3 8 16 3 9 23 4 8 16 4 9 23 4 8 18 4 10 4 8 21 4 10 4 9 31 5 11 4 9 5 11 4 10 5 12 Source: Data provided courtesy of Chandana Reddy, M.S.

May we conclude, on the basis of these data, that the median AUA index in the Flomax® group differs significantly from the median AUA index of the placebo group? Let a ¼ :05.