9.9 Refer to the clinical trials data inTable 10.8 available at the text web site, which are...

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9.9 Refer to the clinical trials data inTable 10.8 available at the text web site, which are analyzed with random effects models in Section 10.3.2. Use GEE methods to analyze the data from the 41 centers, treating each center as a cluster.

a. Specify a working correlation and fit a model.

b. Explain how to compare the two surgeries with a confidence interval.

Interpret.

c. Show how results compare to those from using ML with a model that treats all observations as independent and has additive center and treatment effects.

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