Dr. Out on a limbs claim to fame is her discovery of forgettin, a protein predominantly made

Question:

Dr. Out on a limb’s claim to fame is her discovery of forgettin, a protein predominantly made by the pineal gland in human teenagers. The protein causes selective, short-term unresponsiveness and memory loss when the auditory system receives statements like “Please take out the garbage!” Her hypothesis is that forgettin' has a hydrophobic ER signal sequence at its C-terminus that is recognized by an SRP and causes it to be translocated across the ER membrane by the mechanism shown in Figure 15–14. She predicts that the protein is secreted from pineal cells into the bloodstream, from where it exerts its devastating systemic effects. You are a member of the committee deciding whether she should receive a grant for further work on her hypothesis. Critique her proposal, and remember that grant reviews should be polite and constructive.

Figure 15–14