How is it possible that a change in a single amino acid in a protein of 1000

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How is it possible that a change in a single amino acid in a protein of 1000 amino acids can destroy protein function, even when that amino acid is far away from any ligand binding site?

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Essential Cell Biology

ISBN: 9780393680362

5th Edition

Authors: Bruce Alberts, Karen Hopkin, Alexander Johnson, David Morgan, Martin Raff, Keith Roberts, Peter Walter

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