Which of the following statements are correct? Explain your answers.

A. A bacterial replication fork is asymmetrical because it contains two DNA polymerase molecules that are structurally distinct.

B. Okazaki fragments are removed by a nuclease that degrades RNA.

C. The error rate of DNA replication is reduced both by proofreading by DNA polymerase and by DNA mismatch repair.

D. In the absence of DNA repair, genes become less stable. 

E. None of the aberrant bases formed by deamination occur naturally in DNA.

F. Cancer can result from the accumulation of mutations in somatic cells.