How many infants with at least one birth defect would we expect among the 837 IVF infants if the true prevalence of at least one birth defect in the IVF group were the same as for infants conceived naturally? 

Pediatrics

A study was recently published in Western Australia on the relationship between method of conception and prevalence of major birth defects (Hansen et al. [8]). The

prevalence of at least one major birth defect among infants conceived naturally was 4.2%, based on a large sample of infants. Among 837 infants born as a result of invitro fertilization (IVF), 75 had at least one major birth defect.