Plot the statistical power versus the true efficacy. Do you think 100 patients is a sufficiently large
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Plot the statistical power versus the true efficacy. Do you think 100 patients is a sufficiently large sample to discover whether the new drug is “significantly better” if the true efficacy of the drug is 90%? Why or why not?
Infectious Disease
Suppose a standard antibiotic kills a particular type of bacteria 80% of the time. A new antibiotic is reputed to have better efficacy than the standard antibiotic. Researchers propose to try the new antibiotic on 100 patients infected with the bacteria. Using principles of hypothesis testing (covered in Chapter 7), researchers will deem the new antibiotic “significantly better” than the standard one if it kills
the bacteria in at least 88 out of the 100 infected patients.
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