Repeat the analyses in Problem 12.67 for the mean change in TBUT at 5 minutes post-instillation vs. baseline?

Data from 12.67

Use mixed effects methods to compare the mean change in TBUT immediately post-instillation against baseline according to participant (1, 2, . . . , 14) and nonblink time period (3 sec vs. 6 sec vs. 10 sec). For this analysis, average the first and second replicates and right and left eyes for each participant. Thus, each participant is represented by an average of four values. (Hint: Represent the participant effect as a random effect and the nonblink time-period effect as a fixed effect represented by a set of 2 dummy variables. If there are overall significant differences
for the nonblink time period, then identify which nonblink time periods are significantly different.