To assess the variability of the assay, the investigators need to compute the coefficient of variation. Compute

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To assess the variability of the assay, the investigators need to compute the coefficient of variation. Compute the coefficient of variation (CV) for each subject by obtaining the mean and standard deviation over the 2 replicates for each subject?


Cardiovascular Disease
Activated-protein-C (APC) resistance is a serum marker that has been associated with thrombosis (the formation of blood clots often leading to heart attacks) among adults. A study assessed this risk factor among adolescents. To assess the reproducibility of the assay, a split-sample technique was used in which a blood sample was provided by 10 people; each sample was split into two aliquots (sub-samples), and each aliquot was assessed separately. Table 2.19 gives the results.

Table 2.19: APC resistance split-samples data

Sample number A A-B 2.22 1.88 0.34 3.42 3.59 -0.17 3 3.68 3.01 0.67 0.27 2.64 2.37 0.42 2.68 2.26 3.29 3.04 0.25 0.28 3.

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