What method of analysis can be used to compare the proportion of adverse events between cases and controls? 

Hospital Epidemiology

Death of a patient in the hospital is a high-priority medical outcome. Some hospital deaths may be due to inadequate care and are potentially preventable. An adverse event during a hospital stay is defined as a problem of any nature and seriousness experienced by a patient during his or her stay in the hospital that is potentially attributable to clinical or administrative management rather than the underlying disease. A study in a hospital in Granada, Spain, assessed whether there was a relationship between adverse events and deaths during hospital stay [18]. In this study, 524 cases (i.e., people who died in the hospital) were identified between January 1, 1990, and January 1, 1991. For each case, a control patient was matched on admission diagnosis and admission date. A retrospective chart review determined occurrence of adverse events among all cases and controls. There were 299 adverse events occurring among the cases and 225 among the controls. Among the 299 cases in which an adverse event occurred, 126 of their corresponding matched controls also had an adverse event.