127 Treatments for panic disorder. Inositol is a complex cyclic alcohol found to be effective against clinical depression.

Medical researchers believe that inositol may also be used to treat panic disorder. To test this theory, a doubleblind, placebo-controlled study of 21 patients diagnosed with panic disorder was conducted ( American Journal of Psychiatry, July 1995). Patients completed diaries recording the occurrence of their panic attacks. The data (saved in the INOSITOL file) for a week in which patients received a glucose placebo and for a week when they were treated with inositol are provided in the next table. [ Note:

Neither the patients nor the treating physicians knew which week the placebo was given.] Analyze the data and interpret the results. Comment on the validity of the assumptions.

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Patient Placebo Inositol Patient Placebo Inositol 01320STALO3 O2010026. 12345678901 12 0 2 13 3 1 14 3 1 15 3 4 16 4 2 5 17 6 4 18 15 21 4 19 28 8 1 20 30 0 1 21 13 1 Based on Benjamin, J. "Double-blind, placebo-controlled, crossover trial of inositol treatment for panic disorder." American Journal of Psychiatry, Vol. 152, No. 7, July 1995, p. 1085 (Table 1).