You are asked to prepare a KH 2 PO 4 Na 2 HPO 4 solution that has the same pH as human blood, 7 40 (a) What should be the ratio of concentrations HPO 4 2 H 2 PO 4 in this solution (b) Suppose you have to prepare 1 00 L of the solution described in part (a) and that this solution must be isotonic wi...

Part a The pH of a buffer solution can be calculated using the HendersonHasselbalch equation pH pKa logAHA where pH is the pH of the solution pKa is t ...

You are asked to prepare a KH 2 PO 4 Na 2 HPO 4 solution that has

Question:

You are asked to prepare a KH₂PO₄–Na₂HPO₄ solution that has the same pH as human blood, 7.40.

(a) What should be the ratio of concentrations [HPO₄^2-]/[H₂PO₄^-] in this solution?

(b) Suppose you have to prepare 1.00 L of the solution described in part (a) and that this solution must be isotonic with blood (have the same osmotic pressure as blood). What masses of KH₂PO₄ and of Na₂HPO₄ · 12H₂O would you use? Recall that a solution of NaCl with 9.2 g NaCl/L solution is isotonic with blood, and assume that NaCl is completely ionized in aqueous solution.

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