Ruthenium(II) complexes of the general type shown below are potential anticancer drugs: The cytotoxicity of such complexes

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Ruthenium(II) complexes of the general type shown below are potential anticancer drugs:

The cytotoxicity of such complexes relies upon the replacement of the chlorido ligand by H₂O, and is pH dependent.

(a) Write an equilibrium that defines the K_a value of the hydrolysis product of the above complex.

(b) How does the introduction of electron withdrawing substituents into the arene ring affect the pK_a value of the complex?

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Inorganic Chemistry

ISBN: 9781292134147

5th Edition

Authors: Catherine Housecroft

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Question Posted: Jul 26, 2023 04:24 AM

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Ruthenium(II) complexes of the general type shown below are potential anticancer drugs: The cytotoxicity of such complexes

Question:

N Ru mch N N.N'-bidentate ligand n+

Step by Step Answer:

a The hydrolysis of the rutheniumII complex shown above can be represented by the following equilibr...View the full answer

Inorganic Chemistry

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