In the paper it states that “In this large, long-term trial of male physicians…vitamin C supplementation [did not] reduce the risk of major cardiovascular events. These data provide no support for the use of [vitamin C] for the prevention of cardiovascular disease in middle-aged and older men.” Why do you think the authors specifically qualified their conclusion to say “middle-aged and older men?"

The Physicians’ Health Study II was a randomized, double-blind, placebo- controlled … trial of … vitamin C that began in 1997 and continued until its scheduled completion on August 31, 2007. There were 14,641 US male physicians enrolled, who were initially aged 50 years or older.