Recall Exercise 5.2.11 about the link between babies being large for gestational age (LGA) and gestational diabetes in the mother. In an article published in the New England Journal of Medicine (October 2009), researchers Landon et al. reported on a study of 958 women diagnosed with mild gestational diabetes between 24 and 31 weeks of pregnancy who were randomly assigned to one of two groups: 473 to usual prenatal care (control group) and 485 to dietary intervention, self-monitoring of blood glucose, and insulin therapy, if necessary (treatment group). Of the 473 womenin the control group, 68 had babies who were LGA, and of  the 485 women in the treatment group, 29 had babies who were LGA.
a. Define (in words) the parameters of interest of this study. Also, assign symbols to the parameters.
b. State the appropriate null and alternative hypotheses in words.
c. State the appropriate null and alternative hypotheses in symbols.
d. Explain why it is valid to use the theory-based approach to test the hypotheses stated above.

e. Use an appropriate applet to find a theory-based p-value to test the above hypotheses. Report the standardized statistic as well as the p-value.
f. Use an appropriate applet to find a theory-based 95% confidence interval and interpret the resulting interval in the context of the study.
g. Based on your findings, state a complete conclusion
about the study. Be sure to address significance, estimation, causation, and generalization.
h. Recall that the formula for the standardized statistic in this scenario is

Plug in relevant numbers into this formula and verify the value of the standardized statistic obtained using the applet.
i. Recall that the formula for the confidence interval in this scenario is

Plug in relevant numbers into this formula and verify the value of the 95% confidence interval obtained using the applet.

Data from exercise 5.2.11

A baby weighing more than 4,000 g at birth is considered to be large for gestational age (LGA). Gestational diabetes in the mother is believed to be a common risk factor for LGA. In an article published in the New England Journal of Medicine (October 2009), researchers Landon et al. reported a study of 958 women diagnosed with mild gestational diabetes between 24 and 31 weeks of pregnancy who volunteered toparticipate in the study and then were randomly assigned to  one of two groups: 473 to usual prenatal care (control group) and 485 to dietary intervention, self- monitoring of blood glucose, and insulin therapy, if necessary (treatment group). Of the 473 women in the control group, 68 had babies who were LGA, and of the 485 women in the treatment group, 29 had babies who were LGA.

Transcribed Image Text:

P2 P(1 – p) п,) (Pi(1 – P1) , P2(1 - .) Pi - P2 + multiplier X п п2