Manufacturing Productivity Measures. Alvarez Biological Enterprises is a company located in San Jose, Costa Rica, that produces various blood products for use by hospitals throughout Central America. According to the operations manager, Ricardo Odio, the process for producing a blood coagulant used for treating hemophiliacs is as follows:

A typical batch of plasma transported to the fractionation plant weighs 80 kilograms. Of this, about half results in cryoprecipitate; the other half-a liquid residue-is transformed into other blood products. When the cryoprecipitate is inspected, about two kilograms are typically sent back to the beginning of the centrifugation procedure.
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1. Classify the preceding activities into the five categories of throughput time.
2. Compute the manufacturing (processing) cycle efficiency for the entire process.
3. Compute the first-pass yield for the cryoprecipitate.

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Procedure Blood is drawn from a donor at a clinic. Blood is tested .... Placing into proper blood group Blood is separated into red cell concentrate and plasma Waiting for delivery of plasma to fractionation plant. Transportation to fractionation plant... Incoming plasma 's shelved.... Plasma sits on shelf... Average Time Required 20 minutes 30 minutes 10 minutes 45 minutes 2.5 hours 15 minutes 20 minutes 35 minutes Plasma is taken to centrifugation center Plasma is pooled into batches, prepared, and centrifuged Solids (cryoprecipitate) are processed further.. Cryoprecipitate is frozen Cryoprecipitate waits for inspect on 5 minutes 1.5 hours 2 hours 25 minutes 15 minutes Cryoprecipitate is inspected.. Heat treatment Movement to packaging center Packaging... Completed coagulant is taken to storage area Waiting for delivery to hospital 10 minutes 10 minutes 5 minutes 15 minutes 5 minutes 3 hours