The authors of the article Adjuvant Radiotherapy and Chemotherapy in Node- Positive Premenopausal Women with Breast Cancer

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The authors of the article “Adjuvant Radiotherapy and Chemotherapy in Node- Positive Premenopausal Women with Breast Cancer” (New Engl. J. Med. 1997: 956–962) reported on the results of an experiment designed to compare treating cancer patients with only chemotherapy to treatment with a combination of chemotherapy and radiation. Of the 154 individuals who received the chemotherapy-only treatment, 76 survived at least 15 years, whereas 98 of the 164 patients who received the hybrid treatment survived at least that long.

a. With pdenoting the proportion of all such women who, when treated with just chemotherapy, survive at least 15 years and pdenoting the analogous proportion for the hybrid treatment, calculate a 99% CI for p– p2.

b. Based on the interval from part (a), can either treatment be judged superior to the other? Why or why not?

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Modern Mathematical Statistics With Applications

ISBN: 9783030551551

3rd Edition

Authors: Jay L. Devore, Kenneth N. Berk, Matthew A. Carlton

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