Monomeric single-pass transmembrane proteins span a membrane with a single helix that has characteristic chemical properties

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Monomeric single-pass transmembrane proteins span a membrane with a single α helix that has characteristic chemical properties in the region of the bilayer. Which of the three 20-amino-acid sequences listed below is the most likely candidate for such a transmembrane segment? Explain the reasons for your choice. (See back of book for one-letter amino acid code; FAMILY VW is a convenient mnemonic for hydrophobic amino acids.)

A. I T L I Y F G V M A G V I G T I L L I S
B. I T P I Y F G P M A G V I G T P L L I S
C. I T E I Y F G R M A G V I G T D L L I S

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Molecular Biology Of The Cell

ISBN: 9780815344322

6th Edition

Authors: Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter

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