Exercise 1.2 introduced a study exploring the effect of antibiotic treatment for acute sinusitis. Study participants either received either a 10-day course of an antibiotic (treatment) or a placebo similar in appearance and taste (control). At the end of the 10-day period, patients were asked if they experienced improvement in symptoms. What are the explanatory and response variables in this study?

Data from Exercise 1.2

Researchers studying the eect of antibiotic treatment for acute sinusitis compared to symptomatic treatments randomly assigned 166 adults diagnosed with acute sinusitis to one of two groups: treatment or control. Study participants received either a 10-day course of amoxicillin (an antibiotic) or a placebo similar in appearance and taste. The placebo consisted of symptomatic treatments such as acetaminophen, nasal decongestants, etc. At the end of the 10-day period, patients were asked if they experienced improvement in symptoms. The distribution of responses is summarized below.

Group Treatment Control Total Self-reported improvement in symptoms Yes 66 65 131 No 19 16 35 Total 85 81 166