A male mouse that is heterozygous for a reciprocal translocation between the X chromosome and an autosome
Question:
A male mouse that is heterozygous for a reciprocal translocation between the X chromosome and an autosome is crossed to a female mouse with a normal karyotype. The autosome involved in the translocation carries a gene responsible for coloration of the fur. The allele on the male’s translocated autosome is wild-type, and the allele on its nontranslocated autosome is mutant; however, because the wild-type allele is dominant to the mutant allele, the male’s fur is wild-type (dark in color). The female mouse has light color in her fur because she is homozygous for the mutant allele of the color-determining gene. When the offspring of the cross are examined, all the males have light fur and all the females have patches of light and dark fur. Explainthese peculiar results.
Step by Step Answer:
Principles of Genetics
ISBN: 978-1119142287
7th edition
Authors: D. Peter Snustad, Michael J. Simmons