Assume that the sequence of a double-stranded DNA shown below is present at one end of a
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Assume that the sequence of a double-stranded DNA shown below is present at one end of a large DNA molecule in a eukaryotic chromosome.
5′-(centromere sequence)-gattccccgggaagcttggggggcccatcttcgtacgtctttgca-3′
3′-(centromere sequence)-ctaaggggcccttcgaaccccccgggtagaagcatgagaaacgt-5′
You have reconstituted a eukaryotic replisome that is active in vitro. However, it lacks telomerase activity. If you isolate the DNA molecule shown above and replicate it in your in vitro system, what products would you expect?
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Principles of Genetics
ISBN: 978-1119142287
7th edition
Authors: D. Peter Snustad, Michael J. Simmons
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