In Drosophila, the variegated phenotype of the white mottled allele is suppressed by a dominant autosomal mutation

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In Drosophila, the variegated phenotype of the white mottled allele is suppressed by a dominant autosomal mutation that knocks out the function of the gene for heterochromatin protein 1 (HP1), an important factor in heterochromatin formation. Flies with the white mottled allele and the suppressor mutation have an almost uniform red color in their eyes; without the suppressor mutation, the eyes are mosaics of red and white tissue. Can you suggest an explanation for the effect of the suppressor mutation?

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Principles of Genetics

ISBN: 978-1119142287

7th edition

Authors: D. Peter Snustad, Michael J. Simmons

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