An anesthesiologist has isolated two proteins A and B that bind together by electrostatic attraction. A has net positive charge and B has net negative charge. In water which has a dielectric constant D= 80 at room temperature, their binding constant K1=1000. What is their binding constant if the medium is trifluoroethanol with a dielectric constant of D=27? Assume that the charges in each protein and the distances between them are the same in water and trifluoroethanol.