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1 0.9 0.8 0.7 0.6 10.5 0.4 0.3 0.2 0.1 Fractional Hb saturation Y(PO) 0 0 10 20 30 40 50 60 70 80 90

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1 0.9 0.8 0.7 0.6 10.5 0.4 0.3 0.2 0.1 Fractional Hb saturation Y(PO) 0 0 10 20 30 40 50 60 70 80 90 100 110 120 PO Oxygen partial pressure, mmHg Blood is being used as a source of O for cells that are growing in a tissue engineered construct. The design assumes that blood enters the device with a pO2 = 95 mmHg and leaves the device with a pO = 25 mmHg. If the cells in the device consume oxygen at a rate of 20 M/s and there are 100 mL of cells, what is the required flow rate Q of the blood in mL/min to meet this oxygen demand

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