1. A sympathomimetic drug taken at acute doses would produce side effects such as

a) sedation and weakness.

b) digestion of food and slowing of heart rate.

c) increased heart rate and vasoconstriction.

d) reduced breathing rate and vasodilation.

2. The intended purpose of brain stimulation techniques (such as transcranial magnetic stimulation) is to treat underlying drug craving and other factors contributing to substance misuse by

a) directly increasing certain neurotransmitters in the brain.

b) altering brain circuitry.

c) preventing relapse by shutting down brain reward centers.

d) altering blood flow in the brain.

3. The precondition of _______ would make heavy amphetamine use particularly dangerous.

1) low blood pressure

2) atherosclerosis

3) depression

4) hypothryroidism

4. What have studies with mutant mice that have a cocaine-insensitive serotonin reuptake transporter (SERT) shown?

a) Serotonin levels do not play a role in cocaine-related reward and reinforcement.

b) Inhibiting serotonergic signaling counteracts cocaine-related reward and reinforcement.

c) The effect of serotonin on reward and reinforcement is not clear.

d) Activation of serotonergic signaling counteracts cocaine related reward and reinforcement.

5. In mice, _______ receptor agonists were shown to reduce the locomotor activity effects of cocaine, while, _______ receptor agonists increased locomotor activity.

a) D1; D2

b) D1; D3

c) D2; D3

d) D3; D2

6. Which statement about cocaine is true?

a) It is a synthesized drug.

b) It is an alkaloid that comes from the leaves of a South American bush.

c) It has a high pH.

d) It can exacerbate altitude sickness.