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1. Among 13,963,753 males and 14,272,325 females, there were 20,734 cases of prostate cancer and 19,107 cases of female breast cancer. Calculate the incidence rates

1. Among 13,963,753 males and 14,272,325 females, there were 20,734 cases of prostate cancer and 19,107 cases of female breast cancer. Calculate the incidence rates of prostate cancer and female breast cancer.

a)Prostate cancer rate was 148.5 per 100,000

b)Female breast cancer rate 133.9 per 100,000

c)All of the above

d) None of the above

2. Below is a 2X2 table reflecting the test results for a new rapid screening blood spot test for Lyme Disease that produces results quickly without the need for laboratory testing. The "truth" in this example is determined through more extensive gold standard laboratory testing. What is the sensitivity of the new screening test?

TRUTH

Screening Test Results

Positive

Negative

Totals

Positive

70

31

101

Negative

11

1149

1160

Totals

81

1180

1261

a)86%

b)97%

c)86 per 100,000

d)69%

3. Below is a 2X2 table reflecting the test results for a new rapid screening blood spot test for Lyme Disease that produces results quickly without the need for laboratory testing. The "truth" in this example is determined through more extensive gold standard laboratory testing. What is the specificity of the new screening test?

TRUTH

Screening Test Results

Positive

Negative

Totals

Positive

70

31

101

Negative

11

1149

1160

Totals

81

1180

1261

a) 97 per 100,000

b) 97%

c) 86%

d) 69%

4. Below is a 2X2 table reflecting the test results for a new rapid screening blood spot test for Lyme Disease that produces results quickly without the need for laboratory testing. The "truth" in this example is determined through more extensive gold standard laboratory testing.

What is the positive predictive value of the new screening test?

TRUTH

Screening Test Results

Positive

Negative

Totals

Positive

70

31

101

Negative

11

1149

1160

Totals

81

1180

1261

a) 86%

b) 69 per 100,000

c) 97%

d) 69%

5. Within Refugee Camp X, the midyear population from Jan. 1, 2010 to Dec. 31, 2010 was 5970 refugees. During that same year, there were 1700 recorded deaths. There were 2200 cases of diagnosed cholera recorded among the refugees during that same year. 800 of the 1700 recorded deaths were directly due to cholera. What was the annual mortality rate in this population of refugees. Express your answer per 1000 people and round to the nearest whole number.

a)285 per 1000 people

b) 134 per 100 people

c) 36%

d) 471 per 1000

6. Within Refugee Camp X, the midyear population from Jan. 1, 2010 to Dec. 31, 2010 was 5970 refugees. During that same year, there were 1700 recorded deaths. There were 2200 cases of diagnosed cholera recorded among the refugees during that same year. 800 of the 1700 recorded deaths were directly due to cholera. What was the cause-specific mortality rate from cholera among this refugee population. Express your answer per 1000 people and round to the nearest whole number.

a)285 per 1000

b)134 per 1000

c)36 per 1000

d)None of the above

7. Within Refugee Camp X, the midyear population from Jan. 1, 2010 to Dec. 31, 2010 was 5970 refugees. During that same year, there were 1700 recorded deaths. There were 2200 cases of diagnosed cholera recorded among the refugees during that same year. 800 of the 1700 recorded deaths were directly due to cholera. What was the case-fatality rate for cholera in this population? Express your answer as a percent (%) and round to the nearest whole number.

Group of answer choices a) 285%

b) 134%

c) 471%

d) 36%

8. An epidemiologist conducted an investigation where 17 studies with a total of 8,345 children were included. All studies compared antigen tests against RT-PCR (gold standard or TRUTH). Overall, studies evaluated eight antigen tests. The pooled overall diagnostic sensitivity and specificity in this population of children was 64.2% (95% CI 57.4% to 70.5%) and 99.1% (95% CI 98.2% to 99.5%), respectively. In symptomatic children, the pooled diagnostic sensitivity was 71.8% (95% CI 58.6% to 78.8%) and the pooled diagnostic specificity was 98.7% (95% CI 96.6% to 99.5%). The pooled diagnostic sensitivity in asymptomatic children was 56.2% (95% CI 47.6% to 68.4%) and the pooled diagnostic specificity was 98.6% (95% CI 97.3% to 99.3%). Based on the above findings we can conclude that:

a) The antigen and the PCR test are both very accurate

b) The antigen test has a statistically significantly higher sensitivity among symptomatic children than among asymptomatic children

d) The antigen test has a very high specificity regardless of symptomatic status

E) The antigen test had statistically significant specificity among asymptomatic children than among symptomatic children

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