Question
1. Data are collected in a clinical trial evaluating a new compound designed to improve wound healing in trauma patients. The new compound is compared
1. Data are collected in a clinical trial evaluating a new compound designed to improve wound healing in trauma patients. The new compound is compared against placebo. After treatment for 5 days with the new compound or placebo, the extent of the wound healing is measured and the data are shown in Table 7-6. Is there a difference in the extent of wound healing by treatment? (Hint: Are treatment and the percent wound healing independent?) Run the appropriate test at a 5% level of significance.
Table 7-6: Data for Practice Problems 1 and 2
Treatment
0-25%
26-50%
51-75%
76-100%
New Compound (n=125)
15
37
32
41
Placebo (n=125)
36
45
34
10
2. Use the data in Problem 1 and pool the data across the treatments into one sample size n=250. Use the pooled data to test whether the distribution of the percent wound healing is approximately normal. Specifically, use the following distribution: 30%, 40%, 20%, and 10%. Run the appropriate test = 0.05.
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