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1. Describe the relationship of positive predictive value with specificity of the test? 2. Describe the relationship of negative predictive value with sensitivity of the

1. Describe the relationship of positive predictive value with specificity of the test?

2. Describe the relationship of negative predictive value with sensitivity of the test?

3. How do we determine pre-test probability?

4. How do we determine which ROC curve is optimal for a disease for which several diagnostic tests are available?

5. Describe the relationship of positive and negative predictive value with disease prevalence?

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