Question
(1): download the human genome below is the open source site to get the human genome data for learning purpose site so no issue to
(1): download the human genome below is the open source site to get the human genome data for learning purpose site so no issue to access and download genome data.
sample data attached below / anyone can access it open source no copyright hence sharing .
http://hgdownload.soe.ucsc.edu/goldenPath/hg38/bigZips/hg38.fa.gz (2): Use the Table browser of the website to obtain human genome annotation. (From the top bar, under Tools, select Table Browser).
https://www.genscript.com/tools/codon-frequency-table. (3): Make the following selection: clade: Mammal genome: Human assembly: Dec. 2013 (GRCH38/hg38) group: Genes and Gene Preditions track: NCBI RefSeq
table: RefSeq All (ncbiRefSeq) (I strongly recommend you to click describe table schema to understand the meaning of the table. This is where I will direct you to if you ask me what does each field of the table mean.) region: genome output file: [make you own selection] and then click get output. (4): Obtain the human codon table from https://www.genscript.com/tools/codon- frequency-table. Note that you need to select Human from Expression Host Organism. (5): Write a script to obtain all protein sequences coded in the human genome. Your output should be in the multiple FASTA format, which looks like: >ID1 Sequence 1... >ID2 Sequence 2... The ID field describes what the sequence is. You should use the concatenation (with colon : as the delimiter) of the RefSeq table name and name2 fields as the ID. For example, for the first record in the RefSeq table, the corresponding ID should be >NM_001276352.2:Clorf141. The sequence field simply records the corresponding sequence, all in one line. For example: MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGS AQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHC LLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR
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