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1. Mathematical models are an important tool in understanding and managing infectious disease epidemics. According to the SIR model (first studied by Kermack & McKendrick

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1. Mathematical models are an important tool in understanding and managing infectious disease epidemics. According to the SIR model (first studied by Kermack & McKendrick in 1927), the expected incidence of a disease in the early stages of an epidemic is approximated by f(t) = k sech (at - ), t20 where k,a and 6 are positive constants and t is the time in days since the start of the disease outbreak. The incidence of a disease is the rate of new cases of the disease per unit time, typically measured as the number of new cases in a single day. f(t) thus represents the expected number of new cases at day t. For simplicity, assume the unrealistic but simple values k = 20000, a = 2,0 = 30, which gives f(t) = 20000 sech? (2t - 30), t > 0. (a) Sketch by hand the graph of y = f(t). The graph should have the correct shape, exact value labels for any intercepts, labels for asymptotes and stationary points. (b) Suppose that 1% of the new disease cases on any given day require hospitalisation, and that the hospital system's capacity can handle at most 10 new hospitalisations per day. Find the exact value of t for which the hospital system is first expected to be over capacity. Then use any device invented after the 19th century to find the day for which this occurs. (c) The expected total reported cases at time t days is given by T(t) = = $s f(u) du. Find an expression for T(t) in terms of t. (d) Suppose that the population consists of 1 million people. According to this model, how many people are expected to remain uninfected by the disease in the long term

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