1. Suppose that probability of having a trait is p, and p = 0.01. If a sample of 100 is recorded to see which ones have the trait, what does that tell us about the sampling distribution of the sample with the gene? what does it tell about the probability that none of them have the trait?

2. If the sample is 10000, what is the approximate probability that there is a positive probability for the fraction of sample with the trait to be negative? Find the upper bound for this.