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1) Test A is used to screen for a specific disease in a given population of 10,000 persons. The data are summarized below. Disease Status

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1) Test A is used to screen for a specific disease in a given population of 10,000 persons. The data are summarized below. Disease Status Screening Status III Healthy Total Positive 792 870 Negative 9,108 9,130 Total 100 9,900 10,000 78 22 Using these data, calculate the following and interpret the results in a sentence. a) Sensitivity b) False Negative Rate c) Specificity d) False Positive Rate e) Positive Predictive Value 1) Negative Predictive Value g) Prevalence of Disease 2) Test B is used to screen for the same disease in a different population of 10,000 persons. The data are summarized below. Disease Status Screening Status Healthy Total Positive 640 1,400 2,040 Negative 360 7,600 7,960 Total 1,000 9,000 10,000 Using these data, calculate the following and interpret the results in a sentence. h) Sensitivity i) False Negative Rate j) Specificity k) False Positive Rate 1) Positive Predictive Value m) Negative Predictive Value n) Prevalence of Disease 3) Based on your answers to # 1 and # 2, which of the two tests is the most accurate? Why? Which of the two tests performs better, that is, yields the greatest proportion of cases in the population screened? Why

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