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1. The concentration of chloride (Cl)is 110mM in the extracellular fluid around a neuron, and the chloride concentration in the intracellular fluid is 11mM. For
1. The concentration of chloride (Cl)is 110mM in the extracellular fluid around a neuron, and the chloride concentration in the intracellular fluid is 11mM. For other ions: [Na+]0= 140mM,[Na+]i=12mM,[K+]0=4mM,[K+]i=150mM. Assume the initial permeabilities of the ions are PK:PNa:PCl=1.0:0.04:0.45. a) What is the resting potential of this cell at 37C ? b) Suppose a synapse caused a significant increase in the permeability to chloride (and only to chloride) in the membrane of this post-synaptic neuron. What is the equilibrium potential of chloride in this situation? c) Compared to the original resting potential, would the postsynaptic potential be a depolarization or a hyperpolarization
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