$1.$ Upgrades and patches to the operating system on the EC$2$ instance?

$2.$ Physical security of the data center?

$3.$ Virtualization infrastructure?

$4.$ EC$2$ security group settings?

$5.$ Configuration of applications that run on the EC$2$ instance?

$6.$ Oracle upgrades or patches If the Oracle instance runs as an Amazon RDS instance?

$7.$ Oracle upgrades or patches If Oracle runs on an EC$2$ instance?

$8.$ S$3$ bucket access configuration