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1. Was the study protocol clearly and adequately described? Strength 2. Was the protocol appropriate for the study purpose? 3. Was the protocol realistic for

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1. Was the study protocol clearly and adequately described? Strength 2. Was the protocol appropriate for the study purpose? 3. Was the protocol realistic for a clinical or real-world setting? Limitation 4. Was the protocol consistently administered to all participants in each group (other than the differences in interventions)? Not Evident 5. Did the researchers take steps to control for extraneous variables? Not Applicable 6. Was the protocol ethical and approved by a Review Board

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